Effect of antiepileptic drug monotherapy on endogenous sex hormonal profile in men and women with epilepsy.

Objective: To assess the alterations of endogenous sex hormone profiles in patients with epilepsy (PWE) on different antiepileptic drug (AED) monotherapies compared to healthy controls and drug naïve PWE (DNPWE).

Methods: Four databases MEDLINE, EMBASE, SCOPUS, and CENTRAL were searched for analytical observational/intervention studies on the assessment of endogenous sex hormones in PWE compared to healthy controls and DNPWE. Two researchers reviewed the title/abstract, and full-text articles for the selection of the studies independently.

Identification of ABC transporter Cdr1 inhibitors of Candida glabrata.

Candida glabrata is one of the most common causes of invasive candidiasis. Rising treatment failures from resistance to current antifungal drugs highlight the need for new antifungals. Overexpression of efflux pump transporter genes is significantly associated with the development of multidrug resistance.

C Product Selectivity by 2D-nanosheet of Layered Zn-doped Cu(OH)(NO)-A Pre-catalyst for Electrochemical CO Reduction.

The natural carbon cycle cannot mitigate and recycle the excess CO in the atmosphere, leading to a continuous rise in the global temperature. Electrochemical conversion of CO is one of the useful methods to utilise this anthropogenic CO and convert it into value-added chemicals. However, this process suffers the challenges of product selectivity and good Faradaic efficiency.

Integration of bioflocculation with anaerobic digestion guided by physicochemical profiling enhances valorization potential of domestic wastewater.

Domestic wastewater is a dilute, variable, and complex carbon source for bioprocessing. Despite various treatment technologies, tailored bioprocessing and profiling studies are needed to fully explore its potential. Efficient integration of bioflocculation with anaerobic digestion (AD) is evaluated as a potential platform for small molecules and biogas recovery.