Characterization of Self-Cured Silicone Oils for Encapsulation of Ultraviolet-C Light-Emitting Diodes.

The effectiveness of ultraviolet-C light-emitting diodes (UVC LEDs) is currently limited by the lack of suitable encapsulation materials, restricting their use in sterilization, communication, and in vivo cancer tumor inhibition. This study evaluates various silicone oils for UVC LED encapsulation. A material aging experiment was conducted on CF1040 (octamethylcyclotetrasiloxane), HF2020 (methyl hydro polysiloxanes), and MF2020-1000 (polydimethylsiloxane) under UVC radiation for 1000 h.

Evaluation of adherence to the Preferred Reporting of CasE Series in Surgery (PROCESS) 2020 guideline in case series describing endovascular management of vein of Galen malformation demonstrates suboptimal reporting practices.

Background: Interventional neuroradiology is a dynamic field with technological advancements constantly driving evolution in clinical practice. Case series provide interventional neuroradiologists the opportunity to describe the clinical implications of novel equipment and techniques almost in real-time, informing broader adoption and directing future research. Complete reporting in case series is vital in enabling readers to detect bias, determine the generalizability of results and replicate study methodology.

Structure-Based Design of Novel TLR7/8 Agonist Payloads Enabling an Immunomodulatory Conjugate Approach.

Dual activation of the TLR7 and TLR8 pathways leads to the production of type I interferon and proinflammatory cytokines, resulting in efficient antigen presentation by dendritic cells to promote T-cell priming and antitumor immunity. We developed a novel series of TLR7/8 dual agonists with varying ratios of TLR7 and TLR8 activity for use as payloads for an antibody-drug conjugate approach. The agonist-induced production of several cytokines in human whole blood confirmed their functional activity.

Correction: The peak viscosity of decaying foam with natural drainage and coarsening.

Correction for 'The peak viscosity of decaying foam with natural drainage and coarsening' by Wei Yu and Jack H. Y. Lo, , 2024, , 4964-4971, https://doi.