HIV - Old Foe with a New Face.

We report a case of a middle aged seropositive male, virologically well suppressed on second line ART (Anti-Retroviral therapy) who presented with a subacute history of neurological symptoms. On imaging and CSF (cerebrospinal fluid) evaluation, he was found to have CD8 encephalitis - a new, rare but treatable entity. To the best of our knowledge, no case has been reported from India.