Ensemble methods for survival function estimation with time-varying covariates.

Survival data with time-varying covariates are common in practice. If relevant, they can improve on the estimation of a survival function. However, the traditional survival forests-conditional inference forest, relative risk forest and random survival forest-have accommodated only time-invariant covariates.

Joint latent class trees: A tree-based approach to modeling time-to-event and longitudinal data.

In this paper, we propose a semiparametric, tree-based joint latent class model for the joint behavior of longitudinal and time-to-event data. Existing joint latent class approaches are parametric and can suffer from high computational cost. The most common parametric approach, the joint latent class model, further restricts analysis to using time-invariant covariates in modeling survival risks and latent class memberships.

An ensemble method for interval-censored time-to-event data.

Interval-censored data analysis is important in biomedical statistics for any type of time-to-event response where the time of response is not known exactly, but rather only known to occur between two assessment times. Many clinical trials and longitudinal studies generate interval-censored data; one common example occurs in medical studies that entail periodic follow-up. In this article, we propose a survival forest method for interval-censored data based on the conditional inference framework.

Survival trees for interval-censored survival data.

Interval-censored data, in which the event time is only known to lie in some time interval, arise commonly in practice, for example, in a medical study in which patients visit clinics or hospitals at prescheduled times and the events of interest occur between visits. Such data are appropriately analyzed using methods that account for this uncertainty in event time measurement. In this paper, we propose a survival tree method for interval-censored data based on the conditional inference framework.

Survival trees for left-truncated and right-censored data, with application to time-varying covariate data.

Tree methods (recursive partitioning) are a popular class of nonparametric methods for analyzing data. One extension of the basic tree methodology is the survival tree, which applies recursive partitioning to censored survival data. There are several existing survival tree methods in the literature, which are mainly designed for right-censored data.