Publications by authors named "J S Schouten"

Objectives: In the intensive care unit (ICU), antibiotics are often given longer than recommended in guidelines. A better understanding of the factors influencing antibiotic therapy duration is needed to develop improvement strategies to effectively address these drivers of excessive duration. This study aimed to explore the determinants of adherence to recommended antibiotic therapy durations among healthcare professionals involved in antibiotic decision-making within the ICU, focusing on multidisciplinary meetings (MDMs).

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Agriculture is a vital industry in New York State, which ranks among the top-producing states for dairy, fruits, and several other commodities. As agriculture depends on the weather and specific climatic conditions, this sector faces extraordinary challenges as New York's climate changes. This chapter explores the many impacts of a changing climate on agriculture, the ways these impacts interact with other challenges that New York farmers and farmworkers face, and opportunities for the agriculture industry to adapt and build resilience.

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Background: Patients with glioma often report language complaints with devastating effect on daily life. Analysing spontaneous speech can help to understand underlying language problems. Spontaneous speech monitoring is also of importance during awake brain surgery: it can guide tumour resection and contributes to maintaining language function.

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Objectives: Evidence on the optimal frequency of laboratory testing during outpatient parenteral antimicrobial therapy (OPAT) is lacking. Therefore, we investigated how often and when laboratory abnormalities occur during OPAT and which factors are associated with these abnormalities.

Methods: We performed a multicenter cohort study in four Dutch hospitals among adult patients receiving OPAT and collected routinely obtained laboratory test results.

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Article Synopsis
  • The study aimed to create a new onco-functional outcome (OFO) classification for glioblastoma patients, combining the goals of complete tumor resection and avoiding functional loss into four categories.
  • Analyzing data from 858 patients over ten years, they found that the OFO classification significantly influenced overall survival (OS) and progression-free survival (PFS) rates, especially in certain tumor types.
  • The results showed that achieving the best outcome (OFO1) was linked to improved survival rates and higher likelihood of receiving additional therapy, particularly with awake craniotomy procedures being more effective in avoiding deficits.
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