Associations of the serum -6 PUFA concentrations with exercise-induced myocardial ischaemia in middle-aged and older men.

-6 PUFA, especially linoleic acid (LA) but also arachidonic acid (AA), have been inversely associated with CHD. However, mechanisms underlying these associations are not fully known. We investigated the associations of the serum concentrations of total -6 PUFA, LA, AA, -linolenic acid (GLA) and dihomo--linolenic acid (DGLA), with the odds of myocardial ischaemia during exercise, a predictor of future cardiac events.

National retrospective registry survey on the epidemiology of sarcoidosis in Finland 2002-2022.

Background: The prevalence of sarcoidosis is known to be high in the Nordic countries. There are no recent research data on the incidence or prevalence of sarcoidosis in Finland. Our aim was to investigate the epidemiology of sarcoidosis in Finland through a retrospective registry-based study.

Factors associated with nonword repetition skills in 4-to 6-year-old deaf and hard-of-hearing and typically hearing children.

Children identified as deaf and hard of hearing (DHH) exhibit an increased risk of speech and language difficulties. Nonword repetition (NWR) is a potential tool for identifying language difficulties in children with limited experience with the target language. In this study, we explored associations between auditory, linguistic, demographic and cognitive factors and NWR performance in DHH children and their typically hearing (TH) peers.

Appendicolith classification: physical and chemical properties of appendicoliths in patients with CT diagnosed acute appendicitis - a prospective cohort study.

Objective: Appendicoliths are associated with a more complicated course of acute appendicitis and failure of non-operative treatment. We aimed to update the appendicolith classification originally described in 1966 and to assess the association of appendicolith characteristics with appendicitis severity.

Design: This prospective predefined MAPPAC-trial (ClinicalTrials.

Fish with slow life-history cope better with chronic manganese exposure than fish with fast life-history.

Animals with different life-history types vary in their stress-coping styles, which can affect their fitness and survival in changing environments. We studied how chronic exposure to manganese sulfate (MnSO), a common aquatic pollutant, affects life-history traits, physiology, and behavior of zebrafish () with two life-history types: fast (previously selected for fast juvenile growth, early maturation, and small adult body size) and slow life histories (selected for slow juvenile growth, late maturation, and large adult body size). We found that MnSO had negative effects on growth and condition factors, but the magnitude of these effects depended on the life-history type.