One-step bioprinting of endothelialized, self-supporting arterial and venous networks.

Advances in biofabrication have enabled the generation of freeform perfusable networks mimicking vasculature. However, key challenges remain in the effective endothelialization of these complex, vascular-like networks, including cell uniformity, seeding efficiency, and the ability to pattern multiple cell types. To overcome these challenges, we present an integrated fabrication and endothelialization strategy to directly generate branched, endothelial cell-lined networks using a diffusion-based, embedded 3D bioprinting process.

Limb Underloading in Walking Transmits Less Dynamic Knee Joint Contact Forces after Anterior Cruciate Ligament Reconstruction.

Introduction: Individuals with anterior cruciate ligament reconstruction (ACLR) often walk with a less dynamic vertical ground reaction force (vGRF), exemplified by a reduced first peak vGRF and elevated midstance vGRF compared to uninjured controls. However, the mechanism by which altered limb loading affects actual tibial plateau contact forces during walking remains unclear.

Methods: Our purpose was to use musculoskeletal simulation to evaluate the effects of first peak vertical ground reaction force (vGRF) biofeedback on bilateral tibiofemoral contact forces relevant to the development of post-traumatic osteoarthritis (OA) in 20 individuals with ACLR.

Assessing the Landscape of AI-Powered Patient Documentation in Dermatology.

Background: The prevalence of burnout among United States (US) dermatologists has surged, reaching 49% in 2023, with a growing volume of bureaucratic tasks (eg, charting, paperwork) the leading factor behind professional fatigue. We seek to explore the competitive landscape and efficacy of AI-powered patient documentation to alleviate burnout among dermatologists by optimizing documentation practices while maintaining accuracy.

Methods: We conducted a review of eighteen AI-powered automated documentation products available in the current healthcare landscape, focusing on their integration with electronic health record (EHR) systems, HIPAA compliance, language support, mobile accessibility, and consumer type.

Nursing home staff's experiences with the implementation of an automated blister packaging system for solid, orally ingestible drugs: a qualitative study in Northern Italy.

Objectives: To explore nursing home (NH) staff's experiences implementing an automated blister packaging system for solid, orally ingestible drugs.

Design: This was a descriptive qualitative study. Semistructured interviews were used for data collection, and qualitative content analysis was applied for data analysis.