Publications by authors named "J S Orringer"
Background: Injectable neurotoxins and fillers are potential options for facial gender affirmation for transgender/nonbinary patients. However, the largest barrier to access is cost/insurance coverage.
Objective: The purpose of this article is to assess the extent to which Affordable Care Act (ACA) silver plans and Medicaid policies cover gender-affirming injectable neurotoxin and filler procedures.
In photoaged human skin, type I collagen fragmentation impairs dermal extracellular matrix (ECM) integrity, resulting in collapsed/contracted fibroblasts with reduced type I procollagen synthesis. Injections of cross-linked hyaluronic acid (CL-HA) reverse these deleterious changes. To investigate the time course and effects of biochemical changes induced by injected CL-HA, particularly whether fibroblast activation leads to accumulation/deposition of dermal collagen, we injected CL-HA into photoaged skin of human participants over 60 years-old and performed biochemical/microscopic analyses of skin samples.
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- Photo-mediated ultrasound therapy (PUT) effectively reduces blood vessel density in skin conditions like port-wine stains, achieving a 73.23% decrease in a chicken model after just one treatment session.
- The treatment selectively targets blood vessels without damaging surrounding skin tissues, as confirmed by various histological analyses conducted over multiple time points post-treatment.
- PUT represents a safer alternative to conventional laser treatments for managing cutaneous vascular malformations, utilizing significantly lower laser fluences.