Mechanosensation of the heart and gut elicits hypometabolism and vigilance in mice.

Interoception broadly refers to awareness of one's internal milieu. Although the importance of the body-to-brain communication that underlies interoception is implicit, the vagal afferent signalling and corresponding brain circuits that shape perception of the viscera are not entirely clear. Here, we use mice to parse neural circuits subserving interoception of the heart and gut.

The Impact of an Orofacial Muscle Strengthening Program on Temporomandibular Muscles and on the Performance of Wind Instrumentalists.

Introduction: Playing a wind instrument is one of the most complex tasks for the musculoskeletal system.

Objective: Verify the effectiveness of a strengthening exercise programme on musical performance and the strength of the temporomandibular muscles.

Methods: The sample was 60 participants (36 men; 24 women), with a mean age of 24.

Coumarins and Hesperetin Inhibit Human Respiratory Syncytial Virus Infection.

Respiratory syncytial virus (RSV) is one of the most prevalent viruses that causes severe acute lower respiratory tract infections (ALRTIs) in the elderly and young children. There is no specific drug to treat RSV, only a broad-spectrum antiviral, ribavirin, which is only used in critical cases. Our research group is investigating antiviral agents of natural origin, such as coumarins and flavonoids, that may help reduce or prevent RSV infection.