Full-Thickness Macular Hole Caused by Acute Subretinal Hemorrhage From Wet Age-Related Macular Degeneration.

To present a case of full-thickness macular hole (MH) that developed in association with acute subretinal hemorrhage from wet age-related macular degeneration (AMD). A retrospective observational review of a single case was performed. An 84-year-old man with wet AMD presented with central vision loss and floaters and was noted to have a subretinal hemorrhage and an associated MH, which subsequently progressed to MH-associated macular detachment.

The Penicillin Allergy Delabeling Program: A Multicenter Whole-of-Hospital Health Services Intervention and Comparative Effectiveness Study.

Background: Penicillin allergies are associated with inferior patient and antimicrobial stewardship outcomes. We implemented a whole-of-hospital program to assess the efficacy of inpatient delabeling for low-risk penicillin allergies in hospitalized inpatients.

Methods: Patients ≥ 18 years of age with a low-risk penicillin allergy were offered a single-dose oral penicillin challenge or direct label removal based on history (direct delabeling).

Gender, financial literacy, and preretirement planning in the UK.

This study uses a two-stage logistic regression model to explore the determinants of retirement planning behavior. A survey of 516 UK women and men of prestate retirement age was used to establish interrelationships between gender, retirement planning, and financial literacy, taking account of attitudinal and expectational variables. Findings confirm lower levels of planning among women, but contrary to previous studies, this study reveals that financial literacy is not significantly related to planning.

Landscape genetics informs mesohabitat preference and conservation priorities for a surrogate indicator species in a highly fragmented river system.

Poor dispersal species represent conservative benchmarks for biodiversity management because they provide insights into ecological processes influenced by habitat fragmentation that are less evident in more dispersive organisms. Here we used the poorly dispersive and threatened river blackfish (Gadopsis marmoratus) as a surrogate indicator system for assessing the effects of fragmentation in highly modified river basins and for prioritizing basin-wide management strategies. We combined individual, population and landscape-based approaches to analyze genetic variation in samples spanning the distribution of the species in Australia's Murray-Darling Basin, one of the world's most degraded freshwater systems.

Historic change in catchment land use and metal loading to Sydney estuary, Australia (1788-2010).

Sydney estuary has a long history of environmental degradation and is one of the most modified water ways in Australia due to a highly urbanised catchment (~77 %) and a high population (4.6 million). The objectives of the present study were to map historical land use change from European settlement (1788) to 2010 to determine catchment evolutionary pathways and to estimate catchment loading (total suspended solids, Cu, Pb and Zn) to the estuary over this period.