Publications by authors named "J S Klausner"
Background: Adult and congenital syphilis rates are rising in the US. The aim of this pre- and post-implementation study was to determine whether implementation of an opt-out laboratory-based and rapid syphilis point-of-care testing program in the emergency department (ED) improves the detection and treatment of syphilis during pregnancy in a high-prevalence region.
Methods: This pre-and post-implementation study was conducted at the University of Texas Health Science Center, Houston, TX.
Article Synopsis
- Millions of people in the U.S. are impacted by STIs each year, leading to serious health consequences like infertility and premature births.
- The review focuses on the epidemiology of four key STIs: C. trachomatis, N. gonorrhoeae, T. pallidum, and HSV, illustrating their effects on individuals and the healthcare system.
- The financial burden of these infections is significant, with C. trachomatis alone causing $824 million in medical costs and substantial loss in quality-adjusted life years (QALYs) for both men and women.
Nucleic acid amplification testing (NAAT) for is unavailable in resource-limited settings. We previously developed a CRISPR-based lateral flow assay for detecting . We aimed to pair that assay with point-of-care DNA extraction, assess performance in clinical urine specimens, and optimize assay kinetics.
View Article and Find Full Text PDFObjectives: Doxycycline prophylaxis shows promise for sexually transmitted infection (STI) prevention, but data primarily come from high-income countries. This study assessed awareness, willingness and factors associated with willingness to use doxycycline for STI prevention among men who have sex with men (MSM) using HIV-PrEP in Vietnam.
Methods: Between January 25 and February 4, 2024, a cross-sectional study recruited males aged ≥18 years who reported sex with men in the past 12 months from 11 PrEP clinics in Hanoi and Ho Chi Minh City.