Publications by authors named "J S Hermida"
Article Synopsis
- SCN5A gene variants are linked to various cardiac electrical disorders, but they can also result in complex phenotypes like overlap syndromes, which haven't been thoroughly studied.
- The study analyzed DNA from over 13,500 patients with a focus on those carrying pathogenic SCN5A variants, finding that most were tied to well-defined conditions like Brugada syndrome and long QT syndrome.
- About 19% of the variants were associated with complex phenotypes, and only a small number (8 out of 9,960 patients) showed a potential link to dilated cardiomyopathies (DCM), suggesting it's a rare association.
Article Synopsis
- The study investigates patients with right bundle branch block (RBBB)-ventricular tachycardia (VT) and arrhythmogenic cardiomyopathy (ACM) by examining ECG characteristics of sinus rhythm (SR) and VT.
- It included 70 patients, revealing that the most common sites of origin for the VTs were primarily in the inferior and lateral walls of the left ventricle (LV), with a good correlation to electro-anatomic mapping (EAM) data.
- The findings highlight frequent abnormalities in SR depolarization and repolarization, which are associated with clinical implications in patients with ACM and RBBB-VT.
What do people in different cultures do when they encounter complex problems? Whereas some cross-cultural research exists about complex problem-solving predictors and performance, the process has rarely been studied. We presented participants from Brazil, Germany, the Philippines, and the United States with two computer-simulated dynamic problems, one where quick action was required - the WinFire simulation - and one where cautious action was required - the Coldstore simulation. Participants were asked to think aloud in their native language while working on these two tasks.
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- The study explores how sodium channel blockers (SCBs) can reveal short-coupled premature ventricular complexes (ScPVCs) in patients suspected of having serious heart issues.
- Out of 335 patients tested, 16 exhibited ScPVCs, which typically occurred a few minutes into the SCB infusion and showed consistent patterns across multiple tests.
- The SCB tests proved essential for detecting dangerous arrhythmias in some patients, and catheter ablation was successful in eliminating these arrhythmias for most.