Publications by authors named "J S Barkun"

Article Synopsis
  • Tranexamic acid is known to reduce bleeding and blood transfusions in various surgeries, but its effectiveness for patients undergoing liver resection due to cancer is uncertain.
  • A multicenter randomized clinical trial involving 1384 patients was conducted to see if tranexamic acid decreases the need for red blood cell transfusions within 7 days after liver surgery.
  • The results showed no significant difference in transfusion rates or blood loss between the tranexamic acid group and the placebo group, and those who received tranexamic acid experienced more complications.
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Introduction: Patients with cirrhosis awaiting liver transplantation (LT) are often frail, and malnourished. The period of time on the waitlist provides an opportunity to improve their physical fitness. Prehabilitation appears to improve the physical fitness of patients before major surgery.

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Article Synopsis
  • The objective was to create the first consensus guidelines for the safety and use of robotics in Hepato-Pancreatic-Biliary (HPB) surgery, while also identifying areas for future research.
  • A multidisciplinary jury, using the Zurich-Danish model, formulated recommendations based on expert panels' responses to key questions and the best available evidence from 285 studies.
  • The results highlighted the feasibility and value of robotic surgery in HPB operations but stressed the need for proper expertise and training, as well as prospective registries for evaluating outcomes in future trials.*
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This forum summarizes the proceedings of the joint European Surgical Association (ESA)/American Surgical Association (ASA) symposium on Quality and Outcome Assessment for Surgery that took place in Bordeaux, France, as part of the celebrations of the 30th anniversary of the ESA. Three presentations focused on a) the main messages from the Outcome4Medicine Consensus Conference, which took place in Zurich, Switzerland, in June 2022, b) the patient perspective, and c) benchmarking were hold by ESA members and discussed by ASA members in a symposium attended by members of both associations.

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Article Synopsis
  • EUS-CDS (endoscopic ultrasound-guided choledochoduodenostomy) was compared to ERCP-M (endoscopic retrograde cholangiopancreatography with metal stenting) for treating malignant distal biliary obstruction in a randomized controlled trial involving patients with specific cancer types.
  • The study found that EUS-CDS had a shorter procedure time and a high technical success rate (90.4%), comparable to ERCP-M (83.1%), with similar rates of stent dysfunction (9.6% vs 9.9%).
  • The results suggest that while EUS-CDS is not superior, it is a safe and efficient alternative to ERCP-M, advocating for its broader use in clinical settings.
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