Influence of approaching tram on behaviour of pedestrians in signalised crosswalks in Poland.

Research done in two Polish cities has uncovered an influence of an approaching tram on pedestrian behaviour. The measurements were done by counting pedestrians waiting for a green signal, crossing on red signal safely, or crossing on red signal taking a risk of being hit by a car, differentiating between pedestrians attempting to board a public transport vehicle and other pedestrians. It was expected, that pedestrian behaviour might be influenced by traffic control predictability, therefore two cities were chosen for the task: Wrocław with fixed time traffic control and Poznań with a majority of traffic responsive traffic signals.

Intrathecal administration of baclofen: the method of choice in the treatment of spasticity.

This article presents principles of Intrathecal Baclofen Therapy. We are informed about general experiences of scientists in IBT. The author provides some basic data of baclofen pump sort, pre-implantation baclofen tests and surgical technique.

Modeling of purine derivatives transport across cell membranes based on their partition coefficient determination and quantum chemical calculations.

Mercaptopurine (6-MP), thioguanine (6-TG), and azathioprine (AZA) are purine antimetabolites introduced as anticancer or immunosuppressive drugs decades ago. Methylated AZA, called MAZA, is among the investigational drugs. The present study compares MAZA to the widely recognized drugs AZA, 6-MP, and 6-TG with respect to the ability of being transported across cell membranes.

Palindromes in proteins.

Palindromes in DNA consist of nucleotides sequences that read the same from the 5'-end to the 3'-end, and its double helix is related by twofold axis. They occur in genomes of all organisms and have various functions. For example, restriction enzymes often recognize palindromic sequences of DNA.

Effects of substituting a OH group by a F atom in D-glucose. Ab initio and DFT analysis.

High-level ab initio and DFT methods up to MP2/6-311++G//B3LYP/6-31G and B3LYP/6-311++G//B3LYP/6-31G levels have been used to assess the relative energies of 17 different structures of D-glucose and 13 different structures of 4-deoxy-4-fluoro-D-glucose. The structures were confirmed to correspond to minima on the potential energy surface at the RHF/6-31G level. Solvation Model 5.