Publications by authors named "J Ryan Shackelford"

A mixed-method, cross-sectional descriptive online survey was used to examine the impact of COVID-19 on faith community nurse (FCN) practice. The seven practice areas for FCNs provided a framework for a 20-question survey comparing their practice pre- and during COVID-19 was completed by 378 FCNs. The top five interventions during COVID were in the areas of spiritual support, health promotion, and advocating for services; a top need was peer support/networking.

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Though faith community nurses (FCNs) serve many roles in churches and communities, little is known about their roles or effectiveness in public health interventions. This systematic review summarizes the literature on recent faith community nursing interventions, examining trends, evaluating rigor, and proposing future research directions. Articles were downloaded from PubMed and CINAHL, and 24 studies were included.

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Cholesterol biosynthesis is a multi-step process involving several subcellular compartments, including peroxisomes. Cells adjust their sterol content by both transcriptional and post-transcriptional feedback regulation, for which sterol regulatory element-binding proteins (SREBPs) are essential; such homeostasis is dysregulated in peroxisome-deficient knockout mice. Here, we compared the regulation of cholesterol biosynthesis in Chinese hamster ovary (CHO-K1) cells and in three isogenic peroxisome-deficient CHO cell lines harboring gene mutations.

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Examples of biological rhythmicity mounted in the first half of the twentieth century, but the nature of biological rhythms - whether they were direct responses to rhythmic environmental stimuli or generated internally by biological clocks or oscillators - remained sharply disputed. When Frank A. Brown Jr.

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