Publications by authors named "J Rustige"

Atrial fibrillation (AF) is a common clinically significant cardiac arrhythmia. This phase 3 randomized, double-blind, placebo-controlled trial assessed the efficacy and safety of vernakalant hydrochloride for the pharmacological conversion of AF to sinus rhythm in patients with recent-onset (>3 hours to ≤7 days) symptomatic AF from the Asia-Pacific region. Patients received an infusion of vernakalant (3 mg/kg) or placebo for 10 minutes.

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Article Synopsis
  • Atrial fibrillation (AF) affects at least 30 million people globally and is associated with significant health risks like strokes, heart failure, and high mortality rates, even with existing treatments.
  • There is a critical need to improve preventive measures and identify treatable causes of AF, as many cases remain undiagnosed or poorly managed.
  • The fifth Atrial Fibrillation Network conference focused on enhancing AF care through collaboration, patient-centered approaches, structured management, quality improvement, and personalized treatment plans, alongside outlining key research priorities for AF.
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In autologous and allogeneic hematopoietic SCT (HSCT) neutropenia may be associated with severe infection. Immunodeficiency associated with GVHD and its treatment in allogeneic HSCT is also a risk for severe infection. In both periods, patients may develop severe sepsis with organ failure.

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