Publications by authors named "J Rungby"
It is not well investigated whether exposure to specific drug classes is associated with COVID-19. We investigated the risk of SARS-CoV-2 infection and severe COVID-19 among healthcare workers according to prescription drug use. We conducted an observational study among Danish healthcare workers.
View Article and Find Full Text PDFPurpose: This paper provides an overview of the Danish Centre for Strategic Research in Type 2 Diabetes (DD2) cohort and biobank, including baseline characteristics of participants enrolled up to 2023, and post-enrollment rates of cardiovascular disease outcomes and mortality.
Methods: Since 2010, the DD2 project has enrolled individuals with type 2 diabetes mellitus (T2DM) recently diagnosed by general practitioners and by hospital-based clinicians across Denmark. Data from questionnaires, clinical examinations, and biological samples are collected at enrollment.
Context: Abnormal brain glucose metabolism may cause cognitive disease in type 2 diabetes, yet the relation between insulin resistance and brain glucose metabolism has not been systematically described.
Objective: We evaluated the impact of metabolic condition (fasting vs insulin stimulation, e.g.
Increased plasma levels of glucagon (hyperglucagonemia) promote diabetes development but are also observed in patients with metabolic dysfunction-associated steatotic liver disease (MASLD). This may reflect hepatic glucagon resistance toward amino acid catabolism. A clinical test for measuring glucagon resistance has not been validated.
View Article and Find Full Text PDFArticle Synopsis
- Obesity and chronic oedema/lymphoedema are related conditions, with this study exploring how increased weight affects chronic oedema in patients with leg swelling.
- The study surveyed 7,397 patients across 38 centers in nine countries, revealing that heavier patients experienced more severe stages of chronic oedema compared to those with normal weight.
- Ten independent factors were linked to increased weight, including diabetes and decreased mobility, suggesting that obesity worsens chronic oedema control and decreases overall quality of life.