[The clinical spectrum of cutaneous neonatal lupus erythematosus].

Background: Neonatal lupus erythematosus (NLE) is an uncommon disease described mainly through isolated case reports and a few published series.

Objective: To examine the clinical and serological spectrum, and course of the disease in neonates with NLE and cutaneous involvement.

Methods: A retrospective study was performed that included all children with NLE that came to the Dermatology Department between 1995 and 2006.

[Tumor necrosis factor receptor-associated periodic syndrome].

Tumoral necrosis factor receptor-associated periodic syndrome (TRAPS) is an autosomal dominantly inherited disease belonging to the hereditary periodic fever syndromes, which are the main subgroup among systemic autoinflammatory diseases. TRAPS is characterized by prolonged and recurrent inflammatory attacks associated with fever and an acute phase reaction. Articular, cutaneous, ocular and abdominal symptoms may also be present.

[Early onset Neurobehçet's disease].

Introduction: Behçet's disease is difficult to diagnose in infancy due to the absence of early clinicopathological pathognomonic symptoms. There have been reports of patients in whom the onset of the disease occurred during the first months of their lives.

Case Report: We describe here the case of a 12-year-old female from Pakistan whose first symptoms appeared at the age of 6 months in the form of fever and skin lesions.