Publications by authors named "J Rodriguez-Pascual"
Firearm-related scenarios can be highly complex, involving multiple shooters, firearms, types of ammunition, victims, and various impact zones. Obtaining the maximum amount of information to connect each piece of the puzzle is crucial for resolving these cases. Currently, new tools are being developed in the forensic field that facilitate both fieldwork and laboratory analysis, enabling the estimation of trajectories, identification of shooters, and more.
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- - This article introduces the BioASQ Synergy research process, designed to improve collaboration between biomedical experts and automated question-answering systems to enhance research outcomes.
- - The process involves experts assessing the answers provided by the systems, and this feedback helps refine the systems while generating new questions, fostering an ongoing dialogue and deeper understanding of emerging issues.
- - Initial results show that experts are satisfied with the quality of answers, indicating the potential of BioASQ Synergy to help researchers effectively navigate and access current findings in the rapidly evolving biomedical field.
Article Synopsis
- Lynch syndrome (LS) carriers develop certain types of tumors characterized by high rates of neoantigens, but information on targetable neoantigens from precancerous lesions is lacking, which is important for vaccine development.
- Researchers sequenced genetic data from various stages of colorectal lesions in LS carriers to identify and rank the top 100 mutated neoantigens, validating their findings using specific laboratory assays.
- The findings showed that while cancers and advanced precancers have numerous neoantigens, precancers exhibit fewer, with a significant proportion of the predicted neoantigens being able to prompt immune responses, suggesting potential for developing targeted vaccines against LS-related precancers and early-stage cancers.
Unlabelled: At present, it is challenging to accurately determine firearm shooting distances in the case that lead-free ammunition is involved, largely because different manufacturers use different primer compositions. Laser-induced breakdown spectroscopy (LIBS) allows the simultaneous detection of multiple elements with high sensitivity and so may represent a solution to this problem. Previous studies have, in fact, demonstrated that LIBS can be used to determine shooting distances when working with gunshot residues from conventional ammunition based on scanning fabric surfaces.
View Article and Find Full Text PDFThe application of Laser-Induced Breakdown Spectroscopy (LIBS) in forensic science has garnered increasing attention. The ability to perform real-time, on-site analysis of Gunshot Residue (GSR) particles and potential elements originating from bullets or projectile cores on various surfaces holds the potential to assist in resolving firearms-related cases. This includes facilitating trajectory determination by locating distinct impact points and identifying the types of ammunition used.
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