Publications by authors named "J Rodriguez-Antiguedad"
Despite recent advances in treatment options, stroke remains a highly prevalent and devastating condition with significant socioeconomic impact. Recanalization therapies, including intravenous thrombolysis and endovascular treatments, have revolutionized stroke management and prognosis, providing a promising framework for exploring new therapeutic strategies. Endothelial dysfunction plays a critical role in the pathophysiology, progression, and prognosis of stroke.
View Article and Find Full Text PDFParkinson's disease (PD) is a neurodegenerative condition that is frequently associated with cognitive disorders. These can arise directly from the primary disease, or be triggered by external factors in susceptible individuals due to PD or other predisposing factors. The cognitive disorders encompass PD-associated cognitive impairment (PD-CI), delirium, PD treatment-associated cognitive side effects, cognitive non-motor fluctuations, and PD-associated psychosis.
View Article and Find Full Text PDFHypomimia is a frequent manifestation in Parkinson's disease (PD) that can affect interpersonal relationships and quality of life. Recent studies have suggested that hypomimia is not only related to motor dysfunction but also to impairment in emotional processing networks. Therefore, we hypothesized that the severity of hypomimia could be associated with performance on a task aimed at assessing facial emotion recognition.
View Article and Find Full Text PDFArticle Synopsis
- - Episodic ataxias (EA) are mostly inherited conditions that involve repeated episodes of ataxia and other movement-related symptoms, often linked to mutations in certain genes like CACNA1A and KCNA1.
- - A systematic review of existing literature examined clinical and genetic data from 717 patients with pathogenic variants to understand genotype-phenotype correlations, revealing significant variability in symptoms.
- - The study suggests that due to this variability, comprehensive genetic testing (like panel, whole exome, or genome sequencing) is recommended for more accurate diagnosis and management of EA.