Publications by authors named "J Ribes"
Unlabelled: The BioFire FilmArray meningitis/encephalitis panel (MEP) was brought to the University of Kentucky in 2016 to aid in the identification of community-acquired meningitis and encephalitis (ME). This panel has shown variable performance with some institutions showing high sensitivity and specificity for many pathogens but others seeing false positives during clinical use. We evaluated the panel's performance using retrospective chart review of patients at the University of Kentucky from October 2016 to September 2022, including 7,551 MEP results.
View Article and Find Full Text PDFBackground/objectives: The relationship between macronutrient intake and cognitive decline in older adults with type 2 diabetes mellitus (T2DM) remains underexplored.
Methods: This cross-sectional study aimed to evaluate the association between the protein-to-carbohydrate energy ratio (%E:P) and cognitive impairment among 192 elderly T2DM patients. Cognitive function was assessed using the Montreal Cognitive Assessment (MoCA) and the Self-Administered Gerocognitive Exam (SAGE), while dietary intake data, including (%E:P), was gathered using a validated semi-quantitative food frequency questionnaire.
Article Synopsis
- A study on 219 older patients with type 2 diabetes aimed to investigate the relationship between liver fibrosis, liver steatosis, and cognitive impairment.
- Results showed that a significant number of patients had mild cognitive impairment (53.88%) or dementia (16.43%), and those with moderate to high risks of liver fibrosis were more likely to have cognitive issues.
- The study concluded that liver fibrosis, indicated by a FIB-4 score greater than 1.54, is linked to cognitive impairment, suggesting it could be a potential biomarker for detecting cognitive decline in older diabetes patients.
Several false positive low serum cryptococcal antigen (SCrAg) reports by lateral flow assay (LFA) were identified in late 2016 at our tertiary care hospital. After the recall and correction of the problem in the reagent, we studied the significance of SCrAg LFA ≤ 1:10 from January 2017 to October 2023. Of 20 patients with 31 samples of SCrAg LFA ≤ 1:10, 14 patients (70%) were classified as true positives, four (20%) were indeterminate, and only two (10%) patients were false positives.
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