Associations and Diagnostic Accuracy of Ultrasound Features in Knee Osteoarthritis: Cross-sectional Results from a Large Community-based Cohort.

Objectives: To determine 1) associations among ultrasound (US) features of knee osteoarthritis (KOA), radiographic KOA (rKOA), and patient-reported symptoms, and 2) diagnostic accuracy of US definitions for rKOA, in a community-based cohort.

Methods: Participants enrolled in the Johnston County Health Study (JoCoHS, 2019-24, n=902) provided demographics, comorbidities, clinical features and symptoms, along with imaging with standardized acquisition and scoring protocols. Logistic regression models provided odds ratios adjusted for age, sex, race, ethnicity, body mass index (BMI), education level, comorbidities, and knee injury for associations among US features and KOA outcomes.

Variance and covariance components of agronomic and quality traits assessed in tetraploid potato and their implications on practical breeding.

Potato is a versatile food crop and major component of human nutrition worldwide. Model calculations and computer simulations can be used to optimize the resource allocation in potato breeding programs but require quantitative genetic parameters. The objectives of our study are to (i) estimate quantitative genetic parameters of the most important phenotypic traits in potato breeding programs, (ii) compare the importance of inter- vs.

Beyond nature, nurture, and chance: Individual agency shapes divergent learning biographies and brain connectome.

Individual choices shape life course trajectories of brain structure and function beyond genes and environment. We hypothesized that individual task engagement in response to a learning program results in individualized learning biographies and connectomics. Genetically identical female mice living in one large shared enclosure freely engaged in self-paced, automatically administered and monitored learning tasks.

Impact of coverage and guest residue on polyproline II helix peptide antifouling.

Unlabelled: Polyproline II (PPII) peptide sequences are recognized as promising biomaterials because of their attractive antifouling properties. However, the mechanisms behind their antifouling behavior have not been fully characterized. In this work we show that PPII peptide coverage, controlled by adsorption time, significantly reduces the fouling of bovine serum albumin (BSA, a model foulant).

Correction to "Scalable Production of Peptides for Enhanced Struvite Formation via Expression on the Surface of Genetically Engineered Microbes".

[This corrects the article DOI: 10.1021/acsmaterialsau.3c00037.