Publications by authors named "J Regis"
Article Synopsis
- A systematic review was conducted to evaluate the use of stereotactic radiosurgery (SRS) specifically in pediatric patients, aiming to inform guidelines by the International Stereotactic Radiosurgery Society (ISRS).
- The study analyzed 68 articles focusing on outcomes for around 400 children with brain tumors and over 5000 with arteriovenous malformations (AVMs) from 1989 to 2021, reporting varying local control rates for different tumor types.
- The findings indicated that SRS demonstrated suitable local control rates for pediatric brain tumors and AVMs, but data availability is limited, leading to the development of ISRS consensus guidelines for its use in this population.
Objective: The International Stereotactic Radiosurgery Society aims to establish evidence-based guidelines for single-fraction stereotactic radiosurgery (SRS) in treating intracranial cavernous malformations.
Methods: We conducted a systematic review following Preferred Reporting Items for Systematic Reviews and Meta-Analyses and Meta-analysis of Observational Studies in Epidemiology guidelines, searching electronic databases up to January 2024 to assess SRS's impact on post-treatment hemorrhage rates. Pooled risk ratios (RRs) and confidence intervals were used to quantify this effect, along with assessments of lesion volume changes, seizure outcomes, and SRS-related adverse effects.
Background: Definition of tumor control and treatment failure after Gammaknife radiosurgery (GKRS) for vestibular schwannoma (VS) is still debated. The lack of knowledge on the dynamics of tumor evolution can lead to misinterpretation and subsequent inappropriate second treatment. The aim of this study was to evaluate the post-GKRS dynamics of evolution of tumor volume, and characterize volumetric patterns.
View Article and Find Full Text PDFEffects on Gait and Balance of VIM Gamma Knife Radiosurgery in Essential Tremor.
Stereotact Funct Neurosurg
October 2024
Introduction: Essential tremor (ET) is the most common movement disorder, characterized by an action tremor in the upper limbs. Neurosurgical techniques targeting the thalamic ventrointermediate nucleus (VIM) including thermocoagulation demonstrated a potential risk for gait and posture worsening. This study evaluates the potential effect of VIM Gamma Knife radiosurgery (GKR) in ET on gait and posture performances.
View Article and Find Full Text PDFBackground: Anterior capsulotomy is one of the therapeutic options for refractory obsessive-compulsive disorder (OCD). Safety and efficacy of Gamma Knife Capsulotomy (GKC) have been demonstrated in the past.
Objective: To characterize changes induced by GKC using a fixel-based analysis (FBA) and possible predictors of efficacy.