Publications by authors named "J Rasmuson"
Background: Preeclampsia is an independent risk factor for vascular diseases. The Postpartum Preeclampsia Clinic (PPPC) intervenes in the first year postpartum to address these risks. This study aims to characterize physicians' understanding and management of the cardiovascular risk associated with preeclampsia and whether this differs in physicians who had a patient attend the PPPC.
View Article and Find Full Text PDFObjectives: To investigate the effectiveness of intravenous immunoglobulin (IVIG) as treatment for COVID-19 in immunocompromised patients.
Methods: This retrospective study investigated outcomes for immunocompromised, vaccine non-responsive, patients that between September 2022 and April 2023 received IVIG as treatment for COVID-19 in the region of Västerbotten, Sweden. We analyzed clinical data, viral load, and anti-SARS-CoV-2 IgG binding and neutralization levels of patient serum samples and IVIG production batches.
Background: Anakinra and tocilizumab are used for severe Covid-19, but only one previous randomized controlled trial (RCT) has studied both. We performed a multi-center RCT comparing anakinra or tocilizumab versus usual care (UC) for adults at high risk of deterioration.
Methods: The study was conducted June 2020 to March 2021.
Background: Angiotensin-converting enzyme 2 (ACE2), the receptor for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is highly expressed in the kidneys. Beyond serving as a crucial endogenous regulator of the renin-angiotensin system, ACE2 also possess a unique function to facilitate amino acid absorption. Our observational study sought to explore the relationship between urine ACE2 (uACE2) and renal outcomes in coronavirus disease 2019 (COVID-19).
View Article and Find Full Text PDFArticle Synopsis
- Orthohantaviruses are serious rodent-borne viruses causing diseases like HFRS in Eurasia and hantavirus pulmonary syndrome in the Americas, with significant variation in fatality rates.
- Researchers analyzed a fatal HFRS case linked to a specific strain of Puumala orthohantavirus (PUUV) and found unique mutations in the virus that may influence severity.
- The study revealed that lower levels of neutralizing antibodies and higher viral loads correlated with worse outcomes, suggesting that treatments like bradykinin receptor inhibitors might not be effective for advanced cases.