Publications by authors named "J Ramakrishnan"

Brain tumors can cause difficulties in normal brain function and are capable of developing in various regions of the brain. Malignant tumours can develop quickly, pass through neighboring tissues, and extend to further brain regions or the central nervous system. In contrast, healthy tumors typically develop slowly and do not invade surrounding tissues.

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  • The study aimed to compare the plasma extracellular vesicles (EVs) from Duchenne Muscular Dystrophy (DMD) patients and healthy people using special technology and machine learning.
  • Researchers collected blood samples and used different methods to analyze the size and composition of the EVs.
  • Results showed that DMD patients had unique differences in their plasma EVs, and the researchers developed a model to classify these differences successfully, even with fewer samples.
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  • Urinary tract infections (UTIs) caused by antibiotic-resistant K. pneumoniae are increasing, prompting the need for effective surveillance and management strategies, particularly for high-risk clones.
  • The study aims to analyze the genetic aspects of Klebsiella species, focusing on their resistome (antibiotic resistance genes) and virulome (pathogenicity-related genes), and found significant links between genetic data and observable drug resistance.
  • Findings include the identification of specific fimbrial operons previously associated with Salmonella in K. pneumoniae, the discovery of high genetic diversity within the pangenome, and the recognition of K. pneumoniae kp3 as a carbapenem-resistant and virulent strain, underscoring the
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This research work explores the integration of medical and information technology, particularly focusing on the use of data analytics and deep learning techniques in medical image processing. Specifically, it addresses the diagnosis and prediction of fetal conditions, including Down Syndrome (DS), through the analysis of ultrasound images. Despite existing methods in image segmentation, feature extraction, and classification, there is a pressing need to enhance diagnostic accuracy.

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Diabetes mellitus Type 2 (DM2T) is a rapidly expanding metabolic endocrine disorder worldwide. It is caused due to inadequate insulin secretion by pancreatic beta cells as well as development of insulin resistance. This study aimed to investigate the anti-α-glucosidase, insulin stabilization effect, and non-cytotoxic nature of Gymnema latifolium leaf aqueous extract (GLAE).

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