Publications by authors named "J RUINARD"
Article Synopsis
- Inefficient removal of dying cells and exposure of immune responses to nuclear material contribute significantly to the development of systemic lupus erythematosus (SLE).
- The study examined the role of Factor VII-activating protease (FSAP) in releasing nucleosomes from late apoptotic cells in the serum of SLE patients compared to healthy controls.
- Results showed that SLE patients with high disease activity had reduced nucleosome release, which could be restored by removing certain antibodies, indicating that these antibodies negatively affect the clearance process and may lead to increased inflammation.
