[Long-term therapy of hypertrophic obstructive and non-obstructive cardiomyopathy with nifedipine in comparison to propranolol].

On 24 patients with ascertained hypertrophic obstructive cardiomyopathy and hypertrophic non-obstructive cardiomyopathy in a long-term experiment over 6 months the effect of 30 mg Nifedipin per day on subjective and objective parameters was investigated and compared with Propranolol. The subjective symptoms were in a larger extent improved by Propranolol than by Nifedipin. In contrast to Propranolol Nifedipin had no influence on the systolic function on the basis of the systolic time intervals.

Echocardiographic study of left ventricular posterior wall motion in angina pectoris.

Echocardiographic study of left ventricular posterior wall motion was performed on 22 healthy subjects, on 7 cardiac patients without angina, and on 12 patients with angina pectoris, at rest and during supine exercise on a bicycle ergometer. Resting values did not differ significantly between patients with angina and control subjects. During submaximal ergometric exercise, the systolic excursion of the left ventricular posterior wall as well as the maximal systolic and diastolic velocities increased considerably in all groups.