Reliability and validity of the revised indebtedness scale in Chinese university students.

The purpose of this study was to evaluate the psychometric properties of the Chinese version of the Revised Indebtedness Scale (IS-R-C) in mainland China. A total of 1057 university students participated in this study using a two-wave whole-group sampling method. Sample 1, consisting of 537 participants, was used for item analysis and exploratory factor analysis (EFA) of the Revised Indebtedness Scale (IS-R).

Bioinformatics analysis of miRNAs germacrone protection on diabetic nephropathy.

Diabetes nephropathy (DN) is a prevalent and severe microvascular diabetic complication. Despite the recent developments in germacrone-based therapies for DN, the underlying mechanisms of germacrone in DN remain poorly understood. This study used comprehensive bioinformatics analysis to identify critical microRNAs (miRNAs) and the potential underlying pathways related to germacrone activities.

All-polymer piezo-ionic-electric electronics.

Piezoelectric electronics possess great potential in flexible sensing and energy harvesting applications. However, they suffer from low electromechanical performance in all-organic piezoelectric systems due to the disordered and weakly-polarized interfaces. Here, we demonstrated an all-polymer piezo-ionic-electric electronics with PVDF/Nafion/PVDF (polyvinylidene difluoride) sandwich structure and regularized ion-electron interfaces.

Turning attention to tumor-host interface and focus on the peritumoral heterogeneity of glioblastoma.

Approximately 90% of glioblastoma recurrences occur in the peritumoral brain zone (PBZ), while the spatial heterogeneity of the PBZ is not well studied. In this study, two PBZ tissues and one tumor tissue sample are obtained from each patient via preoperative imaging. We assess the microenvironment and the characteristics of infiltrating immune/tumor cells using various techniques.

Femtomolar hydrogen sulfide detection via hybrid small-molecule nano-arrays.

Early disease diagnosis hinges on the sensitive detection of signaling molecules. Among these, hydrogen sulfide (HS) has emerged as a critical player in cardiovascular and nervous system signaling. On-chip immunoassays, particularly nanoarray-based interfacial detection, offer promising avenues for ultra-sensitive analysis due to their confined reaction volumes and precise signal localization.