Two Patients with Therapy-Resistant Pemphigus Vulgaris and Severe Underlying Disease Showing Good Response to a New IVIg Preparation.

Pemphigus vulgaris is a severe and often therapy-resistant bullous autoimmune disease. Standard therapy with steroids often administered together with another immunosuppressant does not respond in all patients or may not be a good therapeutic option in patients with severe underlying diseases. Intravenous immunoglobulins (IVIgs) represent a treatment alternative, often showing a rapid response which allows one to reduce concomitant immunosuppression.

Measuring dynamic emotional experiences in response to media stimuli.

Communication research has long recognized the dynamic nature of most media stimuli and the corresponding dynamic emotional processing implied on the side of the audience. Capturing and analyzing these emotional dynamics during media reception is imperative for advancing our understanding of media processing and effects, but is not common practice in most communication research. This article highlights several methodological approaches to measuring the physiological, behavioral, and experiential components of emotions during media exposure: Electrodermal activity, automated facial expression analysis, continuous response measurement, and self-probed emotional retrospections.

Patient perspectives on the use of digital medical devices and health data for AI-driven personalised medicine in Parkinson's Disease.

Introduction: Parkinson's Disease (PD) affects around 8.5 million people currently with numbers expected to rise to 12 million by 2040. PD is characterized by fluctuating motor and non-motor symptoms demanding accurate monitoring.

Date palm diverts organic solutes for root osmotic adjustment and protects leaves from oxidative damage in early drought acclimation.

Date palm (Phoenix dactylifera L.) is an important crop in arid regions that is well-adapted to desert ecosystems. To understand the remarkable ability to grow and yield in water-limited environments, experiments with water-withholding for up to four weeks were conducted.

Treatment of a Complex Case of Scleromyxedema Using a Novel Intravenous Immunoglobulin Preparation.

Introduction: We provide a case report on a patient with scleromyxedema treated with high-dose intravenous immunoglobulins (IVIgs) who reported less fatigue and fewer headaches after transitioning to Yimmugo, a novel IVIg preparation. Scleromyxedema is a rare and chronic cutaneous mucinosis, frequently associated with monoclonal gammopathy and systemic complications, which may be life-threatening. The disease is characterized by papular eruptions and sclerosis of the skin.