Publications by authors named "J R Vetter"

Neonatal apneas and hypopneas present a serious risk for healthy infant development. Treating these adverse events requires frequent manual stimulation by skilled personnel, which can lead to alarm fatigue. This study aims to develop and validate an interpretable model that can predict apneas and hypopneas.

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Objective: To assess the correlation between high-resolution microultrasound (microUS) and multiparametric magnetic resonance imaging (MP-MRI) in clinically significant prostate cancer (csPCa) lesion identification.

Methods: We reviewed our prospectively maintained database of 267 consecutive patients who underwent MP-MRI and transperineal microUS-guided biopsy between February 2021 and April 2023. The Prostate Risk Identification using MicroUS (PRI-MUS) protocol was utilized to risk stratify prostate lesions, with PRI-MUS 3-5 defined as positive.

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Denoising diffusion probabilistic models (DDPMs) have recently been shown to accurately generate complicated data such as images, audio, or time series. Experimental and clinical neuroscience also stand to benefit from this progress, as the accurate generation of neurophysiological time series can enable or improve many neuroscientific applications. Here, we present a flexible DDPM-based method for modeling multichannel, densely sampled neurophysiological recordings.

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Objective: We reviewed our institutional experience of radical prostatectomy with and without preoperative multiparametric magnetic resonance imaging (mpMRI) to assess the impact of preoperative prostate mpMRI on surgical outcomes of radical prostatectomy.

Methods: We identified patients at our institution who underwent radical prostatectomy for prostate cancer (PCa) between January 2012 and December 2017 ( = 1044). Using propensity scoring analysis, patients who underwent preoperative mpMRI ( = 285) were matched 1:1 to patients who did not receive preoperative mpMRI ( = 285).

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Article Synopsis
  • Acute myeloid leukemia (AML) is a serious blood cancer that is hard to treat, and scientists are studying a part of the immune system called the NLRP3 inflammasome to understand its role in AML.
  • Researchers looked at gene expressions in AML patients and created special cells to study how NLRP3 affects AML cell survival.
  • They found that higher levels of NLRP3 are linked to worse outcomes for patients, and blocking NLRP3 helps make AML cells die, which could lead to new treatments for the disease.
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