Publications by authors named "J R VAZQUEZ"
Background: Heart failure with preserved ejection fraction (HFpEF) is a heterogeneous entity including patients with different phenotypes of near normal, normal, and supernormal left ventricular (LV) function.
Objectives: To assess the value of resting LV elastance (also known as force) with transthoracic echocardiography (TTE) to identify HFpEF phenotypes.
Methods: In a prospective, observational, multicenter study, 2380 HFpEF patients were recruited from July 2016 to May 2024.
Obesity poses a global health challenge, demanding a deeper understanding of adipose tissue (AT) and its mitochondria. This study describes the role of the mitochondrial protein Methylation-controlled J protein (MCJ/DnaJC15) in orchestrating brown adipose tissue (BAT) thermogenesis. Here we show how MCJ expression decreases during obesity, as evident in human and mouse adipose tissue samples.
View Article and Find Full Text PDFIn the central nervous system, apolipoprotein (APO) E-containing high-density lipoprotein (HDL)-like particles mediate the transport of glial-derived cholesterol to neurons, which is essential for neuronal membrane remodeling and maintenance of the myelin sheath. Despite this, the role of HDL-like cholesterol trafficking on Alzheimer's disease (AD) pathogenesis remains poorly understood. We aimed to examine cholesterol transport via HDL-like particles in cerebrospinal fluid (CSF) of AD patients compared to control individuals.
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- The study investigates the effectiveness of resting-state functional MRI (rs-fMRI) in localizing the seizure onset zone (SOZ) in epilepsy surgery through comparison with other methods like EEG and surgical outcomes.
- Over 9,500 articles were reviewed, leading to 25 that met inclusion criteria, highlighting various comparative modalities, with rs-fMRI showing significant variability in agreement when compared to different methods.
- Results showed that surgical outcomes had better agreement with rs-fMRI than EEG and intracranial EEG, and the study provided meaningful insights into the heterogeneity of SOZ identification using rs-fMRI techniques.
Intersectional Anticipated Discrimination Among Women Experiencing Homelessness in Argentina.
J Community Psychol
January 2025
Women experiencing homelessness constitute a group with idiosyncratic characteristics and needs that have largely remained invisible. Their discriminatory situation has been studied very little which may limit the design of specific intervention strategies. Buenos Aires (Argentina) is one of the main megalopolises in Latin America, where information on women experiencing homelessness is scarcely available.
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