Publications by authors named "J R Sottosanti"

Significance: The arterial input function (AIF) plays a crucial role in correcting the time-dependent concentration of the contrast agent within the arterial system, accounting for variations in agent injection parameters (speed, timing, etc.) across patients. Understanding the significance of the AIF can enhance the accuracy of tissue vascular perfusion assessment through indocyanine green-based dynamic contrast-enhanced fluorescence imaging (DCE-FI).

View Article and Find Full Text PDF
Article Synopsis
  • - Multiple recent articles emphasize the need for outcomes-based and patient-centered guidelines in periodontal therapy.
  • - The authors argue that periodontal treatment should be grounded in evidence-based practices that prioritize the patient's best interests.
  • - They suggest that many patients with periodontal disease are not receiving adequate and timely care for their condition.
View Article and Find Full Text PDF

Following orthopaedic trauma, bone devitalization is a critical determinant of complications such as infection or nonunion. Intraoperative assessment of bone perfusion has thus far been limited. Furthermore, treatment failure for infected fractures is unreasonably high, owing to the propensity of biofilm to form and become entrenched in poorly vascularized bone.

View Article and Find Full Text PDF