Stereotactic trigeminal nucleotomy for dysesthetic facial pain.

Trigeminal nucleotomy is a relatively simple, straightforward stereotactic procedure, acting at the deafferentation site, i.e., at the nucleus caudalis.

Long-term results of stimulation of the septal area for relief of neurogenic pain.

Chronic brain stimulation may be a useful method of treating chronic neurogenic pain. However, the knowledge about the basic mechanisms responsible for pain relief is still fragmentary, and the clinical results have often been inconsistent even contradictory. In an attempt to explore the possibility of stimulating other cerebral targets, stimulating electrodes have been implanted in the septal region in addition to stimulation in the sensory thalamus or the periventricular grey.

Multiloci stereotactic transplantation of autologous adrenal medullary tissue to the putamen and caudatum in Parkinson's disease. Technical note.

Adrenal to striatum transplants may be effective, but many technical issues are still debated. A procedure whereby a number of grafts were stereotactically placed at the putamen and caudatum is reported. It enables grafting deep nuclei, such as the putamen, the most denervated structure in Parkinson's disease, and allows a widespread spatial distribution of multiple grafts within these huge targets, conceivably enhancing the local release of neurotransmitters at the site or in the vicinity of the denervated receptors.

Craniofacial postherpetic neuralgia managed by stereotactic spinal trigeminal nucleotomy.

Postherpetic craniofacial neuralgias are notoriously difficult to deal with. Nevertheless, stereotactic spinal trigeminal nucleotomy seems to be a rational approach, as both experimental and clinical data strongly suggest the relevance of nucleus caudalis for certain facial neurogenic pain phenomena. From a series of 136 consecutive nucleotomies, 80 were performed for deafferentation pain.