Publications by authors named "J R Roman"
Background: Brain-predicted age estimates are used to quantify an individual's brain age compared to a normative trajectory. We have recently shown that brain age from structural MRI is elevated in autosomal dominant Alzheimer disease (ADAD), a unique sample that allows the study of AD progression independently of age-related confounds. Resting-state functional connectivity (FC) may capture a biphasic response to sporadic AD, and thus may complement structural measures of brain aging in ADAD.
View Article and Find Full Text PDFBackground: Brain-predicted age estimates are used to quantify an individual's brain age compared to a normative trajectory. We have recently shown that brain age from structural MRI is elevated in autosomal dominant Alzheimer disease (ADAD), a unique sample that allows the study of AD progression independently of age-related confounds. Resting-state functional connectivity (FC) may capture a biphasic response to sporadic AD, and thus may complement structural measures of brain aging in ADAD.
View Article and Find Full Text PDFA popliteal artery injury in a 12-year-old female patient, injured in the war conflict in Ukraine, proved to be serious, requiring surgical treatment, despite seemingly poor symptoms and the absence of subjective difficulties. The presentation of arterial injury without acute limb ischemia was atypical. The clinical picture of the lower limb in the sense of "pulseless pink" based on an arterial lesion is not common, but its underestimation can have permanent consequences for the patient.
View Article and Find Full Text PDFBackground: Point-of-care HIV viral load testing may enhance patient care and improve HIV health services. We aimed to evaluate the feasibility and acceptability of implementing such testing in a high-volume community sexual health clinic in the United States.
Methods: We conducted a cross-sectional, mixed-methods study.
Article Synopsis
- The rising rates of sexually transmitted infections (STIs) have heightened health concerns, prompting research into doxycycline postexposure prophylaxis (doxyPEP) as a preventive strategy for bacterial STIs.
- A study was conducted in San Francisco to evaluate how the introduction of doxyPEP guidelines affected reported cases of chlamydia, gonorrhea, and early syphilis among men who have sex with men (MSM) and transgender women.
- Results revealed a significant decrease in STI cases among these populations after the implementation of doxyPEP guidelines, with chlamydia and early syphilis cases declining by 6.58% and 2.68% per month, respectively, compared to