Publications by authors named "J R R Carvalho"
Infectious viral pathogens significantly impact wild Leporidae populations, particularly , which was listed as 'Endangered' in 2019. Myxomatosis and rabbit haemorrhagic disease are major contributors to severe epizootics with limited long-lasting immunity. This study expanded beyond these well-documented viruses to include a broader spectrum of viruses in 36 wild rabbit carcasses () collected from the field in 2018, 2019, 2021 and 2024, and 32 wild rabbits hunted in 2017/2018.
View Article and Find Full Text PDFOvarian cancer has the highest mortality rate of all gynecological cancers. Animal models using 7,12-dimethylbenz(a)anthracene (DMBA) have been developed to investigate the mechanisms of ovarian carcinogenesis. The present study is a systematic review of efforts to establish DMBA as a model for ovarian cancer induction in rat models.
View Article and Find Full Text PDFEndophytic Fungi of (Asteraceae): Dereplication of Crude Extracts, Antimicrobial Properties, and Identification of New Tetronic Acid Derivative Produced by .
J Fungi (Basel)
December 2024
Endophytic fungi are increasingly being recognized for their diverse metabolites that may exhibit antimicrobial properties. In our study, we isolated seven endophytic fungal strains from , which were identified as , , , , , and (with two isolates from the same species). Furthermore, the antimicrobial activity of the extracts was assessed, revealing that the extract from demonstrated activity against .
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- The development of tissue engineering arose from a shortage of tissues and damaged organs, with biological scaffolds made from the extracellular matrix (ECM) being a promising solution for transplants.
- Research focused on developing a decellularization protocol for pig ear cartilage, aiming to preserve the ECM's integrity for potential tissue implantation.
- The study found that the best decellularization method combined trypsin, sodium hydroxide, and SDS, while noting that factors like material size and sample thickness influenced the difficulty of the decellularization process.
Inspired by natural microbial cooperation, a co-culture approach was used to synthesize bacterial nanocellulose (BNC)-based nanocomposites for potential wound healing applications. By co-culturing either Komagataeibacter xylinus (K1G4) or the never tested strain K. rhaeticus (K2G46) with the hyaluronic acid (HA)-producer Lacticaseibacillus casei UMCC 2535, two BNC-HA nanocomposites were obtained (C1-K1 and C2-K2).
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