Publications by authors named "J R Melcher"
X-ray diffraction (XRD) is an important material analysis technique with a widespread use of laboratory systems. These systems typically operate at low X-ray energies (from 5 keV to 22 keV) since they rely on the small bandwidth of K-lines like copper. The narrow bandwidth is essential for precise measurements of the crystal structure in these systems.
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- Previous research indicates that school-based physical activity (PA) interventions could positively affect academic performance, particularly in math, but results have been inconclusive due to varying types of PA included in studies.
- The ACTIVE SCHOOL project will implement two distinct PA interventions over one school year and will utilize a randomized controlled trial to assess their impacts on the academic performance of 9-10-year-old children.
- The study aims to gather comprehensive data on various outcomes, such as academic performance, PA levels, cognitive functions, and overall student well-being, to better understand how physical activity influences educational success.
Introduction: Treatment of severe mental illness (SMI) symptoms, especially negative symptoms and cognitive dysfunction in schizophrenia, remains a major unmet need. There is good evidence that SMIs have a strong genetic background and are characterized by multiple biological alterations, including disturbed brain circuits and connectivity, dysregulated neuronal excitation-inhibition, disturbed dopaminergic and glutamatergic pathways, and partially dysregulated inflammatory processes. The ways in which the dysregulated signaling pathways are interconnected remains largely unknown, in part because well-characterized clinical studies on comprehensive biomaterial are lacking.
View Article and Find Full Text PDFObjectives: The purpose of this paper is to present two divergent mental models of integrated advanced liver disease (AdvLD) care among 26 providers who treat patients with AdvLD.
Setting: 3 geographically dispersed United States Veterans Health Administration health systems.
Participants: 26 professionals (20 women and 6 men) participated, including 9 (34.
Optical coherence tomography reveals retinal thinning in schizophrenia spectrum disorders.
Eur Arch Psychiatry Clin Neurosci
April 2023
Background: Schizophrenia spectrum disorders (SSDs) are presumed to be associated with retinal thinning. However, evidence is lacking as to whether these retinal alterations reflect a disease-specific process or are rather a consequence of comorbid diseases or concomitant microvascular impairment.
Methods: The study included 126 eyes of 65 patients with SSDs and 143 eyes of 72 healthy controls.