Publications by authors named "J R Kasprzyk"

Article Synopsis
  • The COAPT Risk Score predicts the likelihood of death or hospitalization for heart failure within two years after undergoing transcatheter edge-to-edge repair for mitral regurgitation using the MitraClip device.
  • An international study analyzed 344 patients categorized as COAPT eligible or non-eligible based on COAPT trial criteria, finding higher risk scores associated with increased mortality and hospitalization.
  • Overall, the COAPT Score had poor predictive accuracy for both groups, showing better performance in lower-risk patients compared to higher-risk patients, suggesting the Score's effectiveness varies according to patient baseline risk.
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Water distribution systems (WDSs) are designed to convey water from sources to consumers. Their operation is a main concern for engineers, researchers, and practitioners and is subject to demand, pressure, and quality constraints. Pumping stations require power to pump water and keep system pressure at a desired level.

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Particulate matter (PM) suspended in the air significantly impacts human health. Those of anthropogenic origin are particularly hazardous. Poland is one of the countries where the air quality during the heating season is the worst in Europe.

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Alcohol and nicotine (tobacco smoke) are often used together, and taking both addictive substances is associated with an increased risk of certain diseases. It is extremely important to understand the pharmacodynamic and pharmacokinetic mechanisms of the interaction between nicotine and ethanol, which are still not fully understood. The study aimed to evaluate the influence of chronic alcohol consumption on nicotine biotransformation in ethanol-preferring and non-preferring male and female rats.

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Short stature is characteristic for Turner syndrome (TS) patients, and particular karyotype abnormalities of the X chromosome may be associated with different responsiveness to recombinant human GH (rhGH) therapy. The aim of the study was to analyze the effect of different types of TS karyotype abnormalities on the response to rhGH therapy. A total of 57 prepubertal patients with TS treated with rhGH with a 3 year follow-up were enrolled in the study and categorized according to their karyotype as X monosomy ( = 35), isochromosome ( = 11), marker chromosome ( = 5), or X-mosaicism ( = 6).

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