QUEST-AI: A System for Question Generation, Verification, and Refinement using AI for USMLE-Style Exams.

The United States Medical Licensing Examination (USMLE) is a critical step in assessing the competence of future physicians, yet the process of creating exam questions and study materials is both time-consuming and costly. While Large Language Models (LLMs), such as OpenAI's GPT-4, have demonstrated proficiency in answering medical exam questions, their potential in generating such questions remains underexplored. This study presents QUEST-AI, a novel system that utilizes LLMs to (1) generate USMLE-style questions, (2) identify and flag incorrect questions, and (3) correct errors in the flagged questions.

Starvation and infection: The role of sickness-associated anorexia in metabolic adaptation during acute infection.

Sickness-associated anorexia, the reduction in appetite seen during infection, is a widely conserved and well-recognized symptom of acute infection, yet there is very little understanding of its functional role in recovery. Anorexic sickness behaviours can be understood as an evolutionary strategy to increase tolerance to pathogen-mediated illness. In this review we explore the evidence for mechanisms and potential metabolic benefits of sickness-associated anorexia.

Paediatric testicular torsion in low- and middle-income countries: an OxPLORE scoping study.

Background: Literature on paediatric surgical conditions in low- and middle-income countries (LMICs) remains limited. As a common emergency, timely treatment of testicular torsion acts as a benchmark of adequate emergency service delivery in paediatric surgery. This scoping study aims to synthesise all existing literature on paediatric testicular torsion in LMICs.