Publications by authors named "J R Hutcheon"

Low iron stores at birth may adversely influence child cognitive and motor development. The aims of this study were to assess cord blood iron levels and explore maternal and neonatal factors associated with iron status. Cord blood specimens (=46) were obtained from the BC Children's Hospital BioBank in Vancouver, Canada.

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  • Chronic or gestational hypertension affects about 7% of pregnancies, and the WILL Trial aimed to find the best timing for delivery to improve outcomes for mothers and babies.
  • The trial involved women with hypertension at 36 to 37 weeks gestation who were randomly assigned to either an early delivery intervention at 38 weeks or usual care at term, analyzing maternal and neonatal outcomes.
  • Despite aiming for 540 participants, the trial ended early with only 403 participants due to slow recruitment, showing no significant difference in poor maternal outcomes between the two groups, while deliveries in the intervention group occurred about 0.9 weeks earlier.
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  • The study focuses on developing a diagnostic model using Quantitative Ultrasound (QUS) to predict pre-eclampsia (PE) and small-for-gestational-age (SGA) outcomes in pregnancies.
  • Researchers collected placenta samples and ultrasound data from women who had cesarean deliveries, measuring key parameters like attenuation and backscatter to create a logistic regression model.
  • The resulting model showed strong predictive ability, with an Area Under the Curve (AUROC) of 0.89, indicating its effectiveness, and future research aims to validate the model with in-utero QUS data.
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Pregnancy weight gain standards are charts describing percentiles of weight gain among participants with no risk factors that could adversely affect weight gain. This detailed information is burdensome to collect. We investigated the extent to which exclusion of various pre-pregnancy, pregnancy and postpartum factors impacted the values of pregnancy weight gain percentiles.

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