Background: In graph theory, M polynomials like the matching polynomial are very crucial in examining the matching structures within graphs, while NM polynomials extends this to analyze non-matching edges. These polynomials are important in many fields, including chemistry and network architecture. They support the derivation of topological indices for protein structure analysis, network communication optimization, and drug design in QSAR/QSPR investigations.
View Article and Find Full Text PDFIndian J Otolaryngol Head Neck Surg
December 2023
Thyroid disorders are the most common endocrine disorder affecting the general population. Diseases of the thyroid glands present with either an alteration of hormone secretion or as an enlargement of the thyroid gland. They vary from non-neoplastic to neoplastic lesions.
View Article and Find Full Text PDFAddiction is a serious public health problem, and the current pharmacotherapy is unable to prevent drug use reinstatement. Studies have focused on physical exercise as a promising coadjuvant treatment. Our research group recently showed beneficial neuroadaptations in the dopaminergic system related to amphetamine-relapse prevention involving physical exercise-induced endogenous opioid system activation (EXE-OS activation).
View Article and Find Full Text PDFBackground: The unrestricted application of antibiotics increased antimicrobial resistance in bacteria through horizontal gene transfer of resistant genes from the pathogenic sources and the evolution of multi-drug resistance organisms. The application of antibiotics caused severe risk to human health because animals may transmit diseases to humans. Hence, the search of novel antimicrobial agents from microbial sources is an urgent need.
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