Physical activity and sedentary behavior have significant prognostic importance in survivors of breast cancer. However, not much is known about physical activity and sedentary behavior in the midwestern United States for patients who have breast cancer. This study provides patient-reported physical activity and sedentary behavior from a cohort of patients from the midwestern United States.
View Article and Find Full Text PDFIntroduction: Premenopausal bilateral oophorectomy (PBO) before the age of 46 years is associated with an increased risk of dementia. We investigated the long-term effects of PBO performed before age 50 years on amyloid beta (Aβ), tau, and neurodegeneration imaging biomarkers of Alzheimer's disease (AD).
Methods: Mayo Clinic Cohort Study of Oophorectomy and Aging-2 participants were divided into early PBO (< 46 years; n = 61), and late PBO (46-49 years; n = 51) groups and were compared to referent women who did not undergo PBO (n = 119).
Background: This study sought to evaluate short- and long-term outcomes of aortic valve (AV) intervention by decalcification or replacement for the treatment of mild to moderate calcific AV stenosis (AS) in patients undergoing transaortic septal myectomy for subaortic left ventricular outflow tract (LVOT) obstruction.
Methods: Between 2000 and 2023, study investigators identified 137 consecutive patients undergoing myectomy with or without membranectomy for mild to moderate calcific AS. Of these patients, 93 underwent surgical intervention on the AV and formed the primary cohort; 44 patients who did not undergo AV intervention were used as a control group.