Tracking Outcomes Post Intensive Care: Findings of a longitudinal observational study.

Background: Many intensive care unit (ICU) survivors experience new or worsening impairments, termed post-intensive care syndrome. Substantial investment has been made in identifying patients at risk and developing interventions, but evidence remains equivocal. A more nuanced understanding of risk and outcomes is therefore warranted.

Sudden Vision Loss: A Diagnostic Approach.

Vision loss affects more than 7 million Americans and impacts quality of life, independence, social functioning, and overall health. Common and dangerous conditions causing sudden vision loss include acute angle-closure glaucoma, retinal detachment, retinal artery occlusion, giant cell arteritis, and optic neuritis. Acute angle-closure glaucoma features ocular pain, headache, and nausea; treatment includes pilocarpine eye drops, oral or intravenous acetazolamide, and intravenous mannitol.

Hospital-level volume in extracorporeal membrane oxygenation cases and death or disability at 6 months.

Objective: Extracorporeal membrane oxygenation (ECMO) is a high-risk procedure with significant morbidity and mortality and there is an uncertain volume-outcome relationship, especially regarding long-term functional outcomes. The aim of this study was to examine the association between ECMO centre volume and long-term death and disability outcomes.

Design Setting And Participants: This is a registry-embedded observational cohort study.

Fusion of Visible and Infrared Aerial Images from Uncalibrated Sensors Using Wavelet Decomposition and Deep Learning.

Multi-modal systems extract information about the environment using specialized sensors that are optimized based on the wavelength of the phenomenology and material interactions. To maximize the entropy, complementary systems operating in regions of non-overlapping wavelengths are optimal. VIS-IR (Visible-Infrared) systems have been at the forefront of multi-modal fusion research and are used extensively to represent information in all-day all-weather applications.

The impact of library size and scale of testing on virtual screening.

Virtual ligand libraries for ligand discovery have recently increased 10,000-fold. Whether this has improved hit rates and potencies has not been directly tested. Meanwhile, typically only dozens of docking hits are assayed, clouding hit-rate interpretation.