Publications by authors named "J R Encarnacion"
Puerto Rican (PR) Hispanic/Latino (H/L) men are an understudied population that has the highest prostate cancer (PCa) specific mortality among other Hispanic populations. Little information is known about the higher mortality in PR H/L men. It is thought that epigenetic changes in key genes may play a critical role in aggressive tumors.
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- Cabotegravir (CAB) is a newly approved HIV treatment and prevention method by the FDA and is crucial in combating the HIV epidemic in the USA.
- Its effectiveness can be affected by specific natural polymorphisms in integrase, especially when combined with primary drug-resistance mutations.
- A study found that the T218I and T218S polymorphisms do not significantly impact CAB's effectiveness, integration, or infectivity, indicating they are unlikely to undermine CAB as a treatment option or pre-exposure prophylaxis.
Introduction: Renal cell carcinoma (RCC) is one of the most common types of kidney cancer. While RCC tends to present as a localized tumor, a notable proportion may present with distant metastasis. In some instances, RCC may also present with intravascular tumor extension, often called tumor thrombus (TT).
View Article and Find Full Text PDFStrategies to strengthen COVID-19 vaccine uptake and improve vaccine equity in U.S. Territories and Freely Associated States during the first six months of vaccine rollout.
Vaccine
September 2024
The eight U.S. territories and freely associated states (TFAS) have historically faced unique social and structural barriers in the implementation of vaccination programs due to geographic remoteness, a high prevalence of socioeconomic disparities, increasing prevalence of natural disasters, limited vaccine providers and clinics, difficulties with procurement and shipping, and difficulty tracking highly mobile populations.
View Article and Find Full Text PDFObjective: Examine whether DNA repair capacity (DRC) levels are associated with body mass index (BMI) in adult women.
Design And Participants: A nested study composed of 539 women without breast cancer (BC) from a case-control BC study in addition to 104 that were recruited later for a total of 643.
Measurements: DRC levels were measured in lymphocytes using a host-cell reactivation assay with a luciferase reporter gene damaged by UVC.