Alcohol septal ablation through an anomalous right coronary septal perforator: first report and discussion.

Alcohol septal ablation has become an acceptable alternative to surgical myectomy in patients with hypertrophic obstructive cardiomyopathy who meet strict clinical and anatomic criteria. While the first septal perforator arising off the left anterior descending artery is the typical conduit for alcohol septal ablation, patients with hypertrophic cardiomyopathy and severe septal hypertrophy may present with unusual septal perforator anatomy, including anomalous origin. We present the case of a patient in whom the dominant basal septal perforator arose anomalously off the proximal right coronary artery.

Immunological analyses of U.S. Space Shuttle crewmembers.

We have previously reported changes in the immunoresponsiveness of "T" lymphocytes following space flight. Additional data collected before and after 11 Shuttle space flights show that absolute lymphocyte numbers, lymphocyte blastogenic capability, and eosinophil percent in the peripheral blood of crewmembers are generally depressed postflight. These responses resemble those associated with physical and emotional stress and may not be related to flight per se.

[Human cellular immune responsiveness following space flight].

Peripheral circulating lymphocytes were separated from astronaut blood samples 3 times before and 2 times after the first four US Space Shuttle flights. The ability of the in vitro T lymphocytes to respond to phytohemagglutinin by blastogenesis was found to be reduced for each crewmember following spaceflight. In addition, the astronauts experienced a postflight increase in neutrophils and a decrease in eosinophils.

Human cellular immune responsiveness following space flight.

Peripheral circulating lymphocytes were separated from astronaut blood samples three times before and two times after the first four US Space Shuttle flights. The ability of the in vitro T lymphocytes to respond to Phytohemagglutinin by blastogenesis was found to be reduced for each crewmember following spaceflight. In addition, the astronauts experienced a postflight increase in neutrophils and a decrease in eosinophils.

Stomatocytosis in a colony of captive squirrel monkeys (Saimiri sciureus).

Chronic stomatocytosis, which increased in severity as a function of the time that animals were held in captivity, was observed in a small colony of squirrel monkeys. The stomatocytosis was associated with increasing hematocrits possibly due to a change in packing characteristics of the erythrocytes rather than any overt changes in the erythrocyte mass. Reticulocytes remained at control levels throughout development of the stomatocytosis.