Publications by authors named "J R Crouse"

Background: Functional impairment is a major concern among those presenting to youth mental health services and can have a profound impact on long-term outcomes. Early recognition and prevention for those at risk of functional impairment is essential to guide effective youth mental health care. Yet, identifying those at risk is challenging and impacts the appropriate allocation of indicated prevention and early intervention strategies.

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Objectives: We examined associations between polygenic risk scores (PRS) for depression (PRS-MDD), psychosis (PRS-SCZ), bipolar disorders (PRS-BD) and neuroticism (PRS-NEU) and (i) help-seeking, and (ii) new onset cases of full-threshold mood or psychotic disorders in youth.

Methods: Help-seeking for mental health problems was assessed by self-report and mood and psychotic disorders were identified using the Composite International Diagnostic Interview. A principal component analysis of the four selected PRS identified two dimensions (BD-SCZ; MDD-NEU) that accounted for 69.

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Onchocerca is an important genus of vector-borne filarial nematodes that infect both humans and animals worldwide. Many Onchocerca spp., most of medical and veterinary health relevance, are the focus of a variety of diagnostic and molecular research.

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Article Synopsis
  • - Moose in boreal habitats are heavily exposed to Dipteran flies, with a study on the Kenai Peninsula revealing that 91% of collected flies were a specific moose fly species, impacting their health.
  • - The study found a positive correlation between the number of sores on moose hind legs and their body fat, indicating that while moose gain energy, they also suffer from injuries caused by flies and parasites.
  • - Interestingly, the presence of flies did not trigger a stress response in moose, as indicated by stable corticosteroid levels, yet the injuries sustained can negatively affect their reproduction and overall survival.
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Article Synopsis
  • - This study explored the impact of filarioid nematodes on northern ungulates, specifically through the detection of their microfilariae in moose blood samples using a new qPCR method.
  • - Researchers collected 166 blood samples from wild moose in Alaska and compared findings from the modified Knott's test and the new qPCR for detecting two types of parasites, achieving a high correlation between the two methods.
  • - The qPCR method showed a detection limit of 0.157 pg/μL of DNA and provided quicker, less labor-intensive results for monitoring these parasites in moose populations.
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