Reformulating the meta-analytical random effects model of the standardized mean difference as a mixture model.

The classical meta-analytical random effects model (REM) has some weaknesses when applied to the standardized mean difference, g. Essentially, the variance of the studies involved is taken as the conditional variance, given a δ value, instead of the unconditional variance. As a consequence, the estimators of the variances involve a dependency between the g values and their variances that distorts the estimates.

Validation and accuracy of the Hyfe cough monitoring system: a multicenter clinical study.

Background: The ability to passively and continuously monitor coughing for prolonged periods of time would significantly improve cough management and research. To date there is no automated clinically validated cough monitor that can be routinely used in clinical care and research. Here we describe the validation of such an automated cough monitor.

Self-awareness interventions after acquired brain injury: A systematic review and meta-analysis.

Objective: Self-awareness (SA) is a crucial component of the neurorehabilitation processes for persons with acquired brain injury. Specific intervention programs to improve SA have been developed and implemented with heterogeneous results. The current study was undertaken to summarize this evidence by conducting a systematic review of relevant literature and to perform a meta-analysis of the most reliable and important results.

The GhANT-GoPGF module regulates pigment gland development in cotton leaves.

Gossypium spp. pigment glands are a good model for studying plant secretory cavity structures. GoPGF (GOSSYPIUM PIGMENT GLAND FORMATION) is a well-characterized master transcription factor that controls gland formation in cotton; however, little is known about its transcriptional regulation.

Regulation of lignin biosynthesis by GhCAD37 affects fiber quality and anther vitality in upland cotton.

Cotton stands as a pillar in the textile industry due to its superior natural fibers. Lignin, a complex polymer synthesized from phenylalanine and deposited in mature cotton fibers, is believed to be essential for fiber quality, although the precise effects remain largely unclear. In this study, we characterized two ubiquitously expressed cinnamyl alcohol dehydrogenases (CAD), GhCAD37A and GhCAD37D (GhCAD37A/D), in Gossypium hirsutum.