How to account for spatial trade-offs in planning for urban climate adaptation? Optimizing green and grey infrastructures.

Urban Nature-Based Solutions have emerged as sound strategies for urban climate change adaptation, but they lack effective decision-support tools. This paper proposes a decision-support framework that relies on Multi-Objective Optimization (MOO), the consideration of actual space availability, the consideration of the simultaneous objectives of climate change adaptation and water management, the integration of demand for co-benefits, and the participatory exploration of trade-offs for decision-makers. The MOO is applied to the case study of the French city of Bordeaux, to identify the optimal location of Groundwater Recharge Infrastructures (GRI) that include Nature-Based Solutions.

Breakthrough infections due to SARS-CoV-2 Delta variant: relation to humoral and cellular vaccine responses.

Introduction: COVID-19 vaccines are expected to provide effective protection. However, emerging strains can cause breakthrough infection in vaccinated individuals. The immune response of vaccinated individuals who have experienced breakthrough infection is still poorly understood.

Does Bariatric Surgery Reduce the Risk of Colorectal Cancer in Individuals with Morbid Obesity? A Systematic Review and Meta-Analysis.

Bariatric surgery has shown to be effective in producing sustained weight loss and the resolution of obesity related medical problems. Recent research focused on the role of obesity and adipose tissue in tumorigenesis, finding a strong crosslink through different mechanisms and highlighting an increase in cancer incidence in individuals with obesity. The aim of this meta-analysis is to find if bariatric surgery reduces the incidence of colorectal cancer in patients with obesity.