Publications by authors named "J R Ayuso Colella"
Amyloidosis is a rare multisystem disorder characterized by extracellular accumulation of insoluble fibrils in various organs and tissues. The most common subtype in the pediatric population is systemic reactive amyloidosis, typically developing secondary to chronic inflammatory conditions and resulting in deposition of serum amyloid A protein in association with apolipoprotein HDL3. Clinical presentation is highly variable and is mostly influenced by specific organs involved, precursor protein type, and extent of amyloid deposition, often closely reflecting clinical features of the underlying disease.
View Article and Find Full Text PDFThat's Not a Hybrid: How to Distinguish Patterns of Admixture and Isolation By Distance.
Mol Ecol Resour
October 2024
Article Synopsis
- Understanding genetic variation is key in studying population genetics and phylogeography, using methods like STRUCTURE for genetic clustering and PCA for analyzing data without model assumptions.
- STRUCTURE can struggle with continuous genetic variation, which can lead to misleading results, highlighting the need for better analysis methods when assessing admixture.
- Combining STRUCTURE and PCA with triangle plots improves the accuracy of inferring demographic history, especially with recent hybridization, and offers robustness against missing data.
Neonatal diabetes mellitus is a rare disorder of glucose metabolism with onset within the first 6 months of life. The initial treatment is based on insulin infusion. The technologies for diabetes treatment can be very helpful, even if guidelines are still lacking.
View Article and Find Full Text PDFArticle Synopsis
- The study evaluates a new technique called Delta Wave Automatic Mapping for effectively identifying ablation sites in patients with Wolff-Parkinson-White Syndrome (WPW) undergoing radiofrequency catheter ablation (RFCA).
- A total of 50 patients were analyzed, with all accessory pathways successfully ablated and a median time-to-effect of 2.0 seconds, showing no recurrences during a follow-up period of about 10 months.
- The workflow eliminates the need for manual site localization by leveraging existing algorithms, relying on specific historical electrical parameters to enhance ablation success and precision.
Community-based policy, systems, and environmental interventions have the potential to reduce modifiable risk factors for obesity early in life. The purpose of this scoping review was to characterize the breadth, generalizability, and methodological quality of community-based diet and obesity-related policy, system, and environmental interventions during the first 1000 days of life, from pregnancy to 24 months of age. Eight databases were searched, and 83 studies (122 references) were included.
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