Publications by authors named "J R Arteaga"
Article Synopsis
- Fluorescent molecules are essential in biomedicine for visualizing biological processes with high sensitivity and specificity, but customizing them for live cell imaging is challenging due to complex structural and photophysical interactions.
- This study used multivariate linear free-energy relationships (mLFER) to optimize a new platform of fluorescent dyes called BASHY, which are derived from boronic acid and salicylidenehydrazone.
- The research resulted in a predictive model for a novel BASHY dye, which demonstrated effective stability in live cell experiments and was tested successfully in zebrafish larvae.
To establish the prevalence of type 2 diabetes, overweight/obesity, and metabolic syndrome in individuals aged >18 years in Bogotá, Colombia and the variables associated with diabetes prevalence. This was a cross‑sectional population survey with a representative, probabilistic sample of Bogotá, Colombia collected between 2022 and 2023. The final sample size included 2,860 households, distributed among 19 localities of Bogotá.
View Article and Find Full Text PDFArticle Synopsis
- A patient with mevalonate kinase deficiency (MKD), an autoinflammatory disease, displayed two gene variants linked to the condition and suffered from recurrent periodic fevers and multiple organ symptoms, particularly a form of kidney disease called IgA nephropathy.
- Despite various immunosuppressive treatments over seven years, the patient found effective relief only after starting canakinumab, a medication targeting inflammation.
- Complications arose from a severe kidney event after an infection, raising questions about how MKD-related inflammation might interact with kidney disease, suggesting a possible connection between the patient's symptoms and underlying disease processes.
Pretreatment of lignocellulosic biomass produces growth inhibitory substances such as furfural which is toxic to microorganisms. Acinetobacter baylyi ADP1 cannot use furfural as a carbon source, instead it biotransforms this compound into difurfuryl ether using the reduced nicotinamide adenine dinucleotide (NADH)-dependent dehydrogenases AreB and FrmA during aerobic acetate catabolism. However, NADH consumption for furfural biotransformation compromises aerobic growth of A.
View Article and Find Full Text PDF