Publications by authors named "J R Angel"

The current study examines cohort (i.e., Generation X, Baby Boomers, and Silent Generation) and gender differences in the stability of Mexican-origin family caregivers over time.

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The pearlspot, Etroplus suratensis is a climate resilient cichlid fish that exhibits unusual adaptation to salinity. The fish is able to complete full life cycle in diverse salinity habitats ranging from fresh water to marine environments. High-quality primary and phased genome assemblies were generated for pearlspot fish using PacBio HiFi and Arima HiC sequencing technologies, for the first time.

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Background: Diffuse midline glioma (DMG) is the most aggressive primary brain tumor in children. All previous studies examining the role of systemic agents have failed to demonstrate a survival benefit; the only standard of care is radiation therapy (RT). Successful implementation of radiosensitization strategies in DMG remains an essential and promising avenue of investigation.

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Article Synopsis
  • Aberrant cell fate transitions can lead to cancer, and p63 is identified as a key factor in determining cell type in esophageal development, specifically between squamous and neuroendocrine lineages.
  • Deleting p63 in developing mice and human stem cells leads to increased neuroendocrine differentiation, suggesting that this transcription factor is crucial for maintaining proper cell identity.
  • In esophageal neuroendocrine carcinoma, p63 is silenced by EZH2-mediated trimethylation, but reactivating p63 can promote a return to squamous cell characteristics, highlighting its role in cancer progression.
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We examined whether religious involvement was associated with cognitive function among older adults in the 2006-2020 waves of the Health and Retirement Study. Using growth curve analysis, we found the association between religious involvement and cognition varied by facet of religious involvement and race and Hispanic ethnicity. Attending religious services with friends was associated with higher initial levels of cognitive function (b = 0.

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